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Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice

Dipeptidyl-peptidase 4 (DPP-4) inhibitor (sitagliptin) is a novel anti-hyperglycemia drug in the treatment of type 2 diabetes. However, its potential in type 1 diabetes is still unclear. Recent studies show that increased infection, especially respiratory tract infection, is significantly associated...

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Detalles Bibliográficos
Autores principales: He, Xinran, Li, Wangen, Xie, Yunliang, Zhao, Yunjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510641/
https://www.ncbi.nlm.nih.gov/pubmed/33182020
http://dx.doi.org/10.1016/j.intimp.2020.106945