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Population Pharmacokinetics of Hydroxychloroquine in COVID-19 Patients: Implications for Dose Optimization

BACKGROUND AND OBJECTIVE: In the absence of characterization on pharmacokinetics and reference concentrations for hydroxychloroquine in COVID-19 patients, the dose and treatment duration for hydrochloroquine are currently empirical, mainly based on in vitro data, and may vary across national guideli...

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Detalles Bibliográficos
Autores principales: Thémans, Pauline, Belkhir, Leila, Dauby, Nicolas, Yombi, Jean-Cyr, De Greef, Julien, Delongie, Kevin-Alexandre, Vandeputte, Martin, Nasreddine, Rakan, Wittebole, Xavier, Wuillaume, Francoise, Lescrainier, Cécile, Verlinden, Veerle, Kiridis, Sophie, Dogné, Jean-Michel, Hamdani, Jamila, Wallemacq, Pierre, Musuamba, Flora T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511144/
https://www.ncbi.nlm.nih.gov/pubmed/32968954
http://dx.doi.org/10.1007/s13318-020-00648-y