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Neurofascin and Kv7.3 are delivered to somatic and axon terminal surface membranes en route to the axon initial segment

Ion channel complexes promote action potential initiation at the mammalian axon initial segment (AIS), and modulation of AIS size by recruitment or loss of proteins can influence neuron excitability. Although endocytosis contributes to AIS turnover, how membrane proteins traffic to this proximal axo...

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Detalles Bibliográficos
Autores principales: Ghosh, Aniket, Malavasi, Elise LV, Sherman, Diane L, Brophy, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511229/
https://www.ncbi.nlm.nih.gov/pubmed/32903174
http://dx.doi.org/10.7554/eLife.60619