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Neurofascin and Kv7.3 are delivered to somatic and axon terminal surface membranes en route to the axon initial segment
Ion channel complexes promote action potential initiation at the mammalian axon initial segment (AIS), and modulation of AIS size by recruitment or loss of proteins can influence neuron excitability. Although endocytosis contributes to AIS turnover, how membrane proteins traffic to this proximal axo...
Autores principales: | Ghosh, Aniket, Malavasi, Elise LV, Sherman, Diane L, Brophy, Peter J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511229/ https://www.ncbi.nlm.nih.gov/pubmed/32903174 http://dx.doi.org/10.7554/eLife.60619 |
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