Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution

The spindle shows remarkable diversity, and changes in an integrated fashion, as cells vary over evolution. Here, we provide a mechanistic explanation for variations in the first mitotic spindle in nematodes. We used a combination of quantitative genetics and biophysics to rule out broad classes of...

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Detalles Bibliográficos
Autores principales: Farhadifar, Reza, Yu, Che-Hang, Fabig, Gunar, Wu, Hai-Yin, Stein, David B, Rockman, Matthew, Müller-Reichert, Thomas, Shelley, Michael J, Needleman, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511230/
https://www.ncbi.nlm.nih.gov/pubmed/32966209
http://dx.doi.org/10.7554/eLife.55877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511230/
https://www.ncbi.nlm.nih.gov/pubmed/32966209
http://dx.doi.org/10.7554/eLife.55877

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