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Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution
The spindle shows remarkable diversity, and changes in an integrated fashion, as cells vary over evolution. Here, we provide a mechanistic explanation for variations in the first mitotic spindle in nematodes. We used a combination of quantitative genetics and biophysics to rule out broad classes of...
Autores principales: | Farhadifar, Reza, Yu, Che-Hang, Fabig, Gunar, Wu, Hai-Yin, Stein, David B, Rockman, Matthew, Müller-Reichert, Thomas, Shelley, Michael J, Needleman, Daniel J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511230/ https://www.ncbi.nlm.nih.gov/pubmed/32966209 http://dx.doi.org/10.7554/eLife.55877 |
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