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Structural Basis for Vital Function and Malfunction of Serum Amyloid A: an Acute-Phase Protein that Wears Hydrophobicity on Its Sleeve
PURPOSE OF REVIEW: This review addresses normal and pathologic functions of serum amyloid A (SAA), an enigmatic biomarker of inflammation and protein precursor of AA amyloidosis, a life-threatening complication of chronic inflammation. SAA is a small, highly evolutionarily conserved acute-phase prot...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511256/ https://www.ncbi.nlm.nih.gov/pubmed/32968930 http://dx.doi.org/10.1007/s11883-020-00888-y |