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Ancestral sequence reconstruction produces thermally stable enzymes with mesophilic enzyme-like catalytic properties

Enzymes have high catalytic efficiency and low environmental impact, and are therefore potentially useful tools for various industrial processes. Crucially, however, natural enzymes do not always have the properties required for specific processes. It may be necessary, therefore, to design, engineer...

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Detalles Bibliográficos
Autores principales: Furukawa, Ryutaro, Toma, Wakako, Yamazaki, Koji, Akanuma, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511310/
https://www.ncbi.nlm.nih.gov/pubmed/32968141
http://dx.doi.org/10.1038/s41598-020-72418-4