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Direct analysis in real time-mass spectrometry for rapid quantification of five anti-arrhythmic drugs in human serum: application to therapeutic drug monitoring

Therapeutic drug monitoring (TDM) is necessary for the optimal administration of anti-arrhythmic drugs in the treatment of heart arrhythmia. The present study aimed to develop and validate a direct analysis in real time tandem mass spectrometry (DART–MS/MS) method for the rapid and simultaneous dete...

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Detalles Bibliográficos
Autores principales: Gui, Yuzhou, Lu, Youli, Li, Shuijun, Zhang, Mengqi, Duan, Xiaokun, Liu, Charles C., Jia, Jingying, Liu, Gangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511339/
https://www.ncbi.nlm.nih.gov/pubmed/32968164
http://dx.doi.org/10.1038/s41598-020-72490-w