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A novel lncRNA LNC_000052 leads to the dysfunction of osteoporotic BMSCs via the miR-96-5p–PIK3R1 axis

Bone marrow-derived mesenchymal stem cells (BMSCs) in postmenopausal osteoporosis models exhibit loss of viability and multipotency. Identification of the differentially expressed RNAs in osteoporotic BMSCs could reveal the mechanisms underlying BMSC dysfunction under physiological conditions, which...

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Detalles Bibliográficos
Autores principales: Li, Mingyang, Cong, Rong, Yang, Liyu, Yang, Lei, Zhang, Yiqi, Fu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511361/
https://www.ncbi.nlm.nih.gov/pubmed/32968049
http://dx.doi.org/10.1038/s41419-020-03006-7