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Terminal differentiation of human granulosa cells as luteinization is reversed by activin-A through silencing of Jnk pathway
Molecular mechanisms underlying luteinization (terminal differentiation of granulosa and theca cells after ovulation) and luteolysis (demise of corpus luteum) are poorly understood in human ovary. Here we report that activin-A, after binding to its cognate receptors induces a functional luteolytic s...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511402/ https://www.ncbi.nlm.nih.gov/pubmed/33042587 http://dx.doi.org/10.1038/s41420-020-00324-9 |