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Terminal differentiation of human granulosa cells as luteinization is reversed by activin-A through silencing of Jnk pathway

Molecular mechanisms underlying luteinization (terminal differentiation of granulosa and theca cells after ovulation) and luteolysis (demise of corpus luteum) are poorly understood in human ovary. Here we report that activin-A, after binding to its cognate receptors induces a functional luteolytic s...

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Detalles Bibliográficos
Autores principales: Bildik, Gamze, Akin, Nazli, Esmaeilian, Yashar, Hela, Francesko, Yildiz, Ceren Sultan, Iltumur, Ece, İncir, Said, Karahuseyinoglu, Sercin, Yakin, Kayhan, Oktem, Ozgur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511402/
https://www.ncbi.nlm.nih.gov/pubmed/33042587
http://dx.doi.org/10.1038/s41420-020-00324-9