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Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion

Although metastatic disease is responsible for the majority of cancer deaths, tests of novel immunotherapies in mouse tumour models often focus on primary tumours without determining whether these therapies also target metastatic disease. This study examined the impact of depleting Foxp3(+) regulato...

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Detalles Bibliográficos
Autores principales: Hughes, Ellyn, Lauder, Sarah N., Smart, Kathryn, Bloom, Anja, Scott, Jake, Jones, Emma, Somerville, Michelle, Browne, Molly, Blainey, Andrew, Godkin, Andrew, Ager, Ann, Gallimore, Awen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511476/
https://www.ncbi.nlm.nih.gov/pubmed/32447412
http://dx.doi.org/10.1007/s00262-020-02603-x