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Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion
Although metastatic disease is responsible for the majority of cancer deaths, tests of novel immunotherapies in mouse tumour models often focus on primary tumours without determining whether these therapies also target metastatic disease. This study examined the impact of depleting Foxp3(+) regulato...
Autores principales: | Hughes, Ellyn, Lauder, Sarah N., Smart, Kathryn, Bloom, Anja, Scott, Jake, Jones, Emma, Somerville, Michelle, Browne, Molly, Blainey, Andrew, Godkin, Andrew, Ager, Ann, Gallimore, Awen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511476/ https://www.ncbi.nlm.nih.gov/pubmed/32447412 http://dx.doi.org/10.1007/s00262-020-02603-x |
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