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How to fix DNA-protein crosslinks

Proteins that act on DNA, or are in close proximity to it, can become inadvertently crosslinked to DNA and form highly toxic lesions, known as DNA-protein crosslinks (DPCs). DPCs are generated by different chemotherapeutics, environmental or endogenous sources of crosslinking agents, or by lesions o...

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Detalles Bibliográficos
Autores principales: Kühbacher, Ulrike, Duxin, Julien P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511601/
https://www.ncbi.nlm.nih.gov/pubmed/32683310
http://dx.doi.org/10.1016/j.dnarep.2020.102924