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Genome-Wide Characterization of Host Transcriptional and Epigenetic Alterations During HIV Infection of T Lymphocytes

Background and methods: Host genomic alterations are closely related to dysfunction of CD4(+) T lymphocytes in the HIV–host interplay. However, the roles of aberrant DNA methylation and gene expression in the response to HIV infection are not fully understood. We investigated the genome-wide DNA met...

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Detalles Bibliográficos
Autores principales: Zeng, Xi, Tsui, Joseph Chi-Ching, Shi, Mai, Peng, Jie, Cao, Cyanne Ye, Kan, Lea Ling-Yu, Lau, Carol Po-Ying, Liang, Yonghao, Wang, Lingyi, Liu, Li, Chen, Zhiwei, Tsui, Stephen Kwok-Wing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511662/
https://www.ncbi.nlm.nih.gov/pubmed/33013899
http://dx.doi.org/10.3389/fimmu.2020.02131