Treatment with Commonly Used Antiretroviral Drugs Induces a Type I/III Interferon Signature in the Gut in the Absence of HIV Infection

Tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) are used for HIV treatment and prevention. Previously, we found that topical rectal tenofovir gel caused immunological changes in the mucosa. Here, we assess the effect of oral TDF/FTC in three HIV pre-exposure prophylaxis trials, two with...

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Detalles Bibliográficos
Autores principales: Hughes, Sean M., Levy, Claire N., Calienes, Fernanda L., Stekler, Joanne D., Pandey, Urvashi, Vojtech, Lucia, Berard, Alicia R., Birse, Kenzie, Noël-Romas, Laura, Richardson, Brian, Golden, Jackelyn B., Cartwright, Michael, Collier, Ann C., Stevens, Claire E., Curlin, Marcel E., Holtz, Timothy H., Mugo, Nelly, Irungu, Elizabeth, Katabira, Elly, Muwonge, Timothy, Lama, Javier R., Baeten, Jared M., Burgener, Adam, Lingappa, Jairam R., McElrath, M. Juliana, Mackelprang, Romel, McGowan, Ian, Cranston, Ross D., Cameron, Mark J., Hladik, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511692/
https://www.ncbi.nlm.nih.gov/pubmed/33015651
http://dx.doi.org/10.1016/j.xcrm.2020.100096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511692/
https://www.ncbi.nlm.nih.gov/pubmed/33015651
http://dx.doi.org/10.1016/j.xcrm.2020.100096

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