Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress

Cells coordinate interphase-to-mitosis transition, but recurrent cytogenetic lesions appear at common fragile sites (CFSs), termed CFS expression, in a tissue-specific manner after replication stress, marking regions of instability in cancer. Despite such a distinct defect, no model fully provides a...

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Detalles Bibliográficos
Autores principales: Boteva, Lora, Nozawa, Ryu-Suke, Naughton, Catherine, Samejima, Kumiko, Earnshaw, William C., Gilbert, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511797/
https://www.ncbi.nlm.nih.gov/pubmed/32966795
http://dx.doi.org/10.1016/j.celrep.2020.108177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511797/
https://www.ncbi.nlm.nih.gov/pubmed/32966795
http://dx.doi.org/10.1016/j.celrep.2020.108177

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