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Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress
Cells coordinate interphase-to-mitosis transition, but recurrent cytogenetic lesions appear at common fragile sites (CFSs), termed CFS expression, in a tissue-specific manner after replication stress, marking regions of instability in cancer. Despite such a distinct defect, no model fully provides a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511797/ https://www.ncbi.nlm.nih.gov/pubmed/32966795 http://dx.doi.org/10.1016/j.celrep.2020.108177 |