Cyclin-Dependent Kinase 9 (CDK9) Inhibitor Atuveciclib Suppresses Intervertebral Disk Degeneration via the Inhibition of the NF-κB Signaling Pathway

Intervertebral disk degeneration (IVDD) is a spinal disk condition caused by an inflammatory response induced by various proinflammatory cytokines, such as interleukin (IL)-1β and tumor necrosis factor (TNF)-α. cyclin-dependent kinase 9 (CDK9) is a transcriptional regulator and potential therapeutic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ni, Weiyu, Zhang, Feizhou, Zheng, Lin, Wang, Lili, Liang, Yi, Ding, Yuhong, Yik, Jasper H. N., Haudenschild, Dominik R., Fan, Shunwu, Hu, Ziang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511812/
https://www.ncbi.nlm.nih.gov/pubmed/33015073
http://dx.doi.org/10.3389/fcell.2020.579658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511812/
https://www.ncbi.nlm.nih.gov/pubmed/33015073
http://dx.doi.org/10.3389/fcell.2020.579658

Ejemplares similares