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Cyclin-Dependent Kinase 9 (CDK9) Inhibitor Atuveciclib Suppresses Intervertebral Disk Degeneration via the Inhibition of the NF-κB Signaling Pathway

Intervertebral disk degeneration (IVDD) is a spinal disk condition caused by an inflammatory response induced by various proinflammatory cytokines, such as interleukin (IL)-1β and tumor necrosis factor (TNF)-α. cyclin-dependent kinase 9 (CDK9) is a transcriptional regulator and potential therapeutic...

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Detalles Bibliográficos
Autores principales:	Ni, Weiyu, Zhang, Feizhou, Zheng, Lin, Wang, Lili, Liang, Yi, Ding, Yuhong, Yik, Jasper H. N., Haudenschild, Dominik R., Fan, Shunwu, Hu, Ziang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511812/ https://www.ncbi.nlm.nih.gov/pubmed/33015073 http://dx.doi.org/10.3389/fcell.2020.579658

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