Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development

The NAD(+)‐dependent sirtuin deacetylase, Sirt1, regulates key transcription factors strongly implicated in ageing and lifespan. Due to potential confounding effects secondary to loss of Sirt1 function from the soma in existing whole‐animal mutants, the in vivo role of Sirt1 in oocytes (oocyte‐Sirt1...

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Detalles Bibliográficos
Autores principales: Iljas, Juvita D., Wei, Zhe, Homer, Hayden A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511857/
https://www.ncbi.nlm.nih.gov/pubmed/32729989
http://dx.doi.org/10.1111/acel.13204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511857/
https://www.ncbi.nlm.nih.gov/pubmed/32729989
http://dx.doi.org/10.1111/acel.13204

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