Cargando…
Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development
The NAD(+)‐dependent sirtuin deacetylase, Sirt1, regulates key transcription factors strongly implicated in ageing and lifespan. Due to potential confounding effects secondary to loss of Sirt1 function from the soma in existing whole‐animal mutants, the in vivo role of Sirt1 in oocytes (oocyte‐Sirt1...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511857/ https://www.ncbi.nlm.nih.gov/pubmed/32729989 http://dx.doi.org/10.1111/acel.13204 |