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FOXO3a acts to suppress DNA double‐strand break‐induced mutations

Genomic instability is one of the hallmarks of aging, and both DNA damage and mutations have been found to accumulate with age in different species. Certain gene families, such as sirtuins and the FoxO family of transcription factors, have been shown to play a role in lifespan extension. However, th...

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Detalles Bibliográficos
Autores principales: White, Ryan R., Maslov, Alexander Y., Lee, Moonsook, Wilner, Samantha E., Levy, Matthew, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511859/
https://www.ncbi.nlm.nih.gov/pubmed/32720744
http://dx.doi.org/10.1111/acel.13184