Body weight and high‐fat diet are associated with epigenetic aging in female members of the BXD murine family

DNA methylation (DNAm) is shaped by genetic and environmental factors and modulated by aging. Here, we examine interrelations between epigenetic aging, body weight (BW), and life span in 12 isogenic strains from the BXD family of mice that exhibit over twofold variation in longevity. Genome‐wide DNA...

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Detalles Bibliográficos
Autores principales: Sandoval‐Sierra, Jose Vladimir, Helbing, Alexandra H. B., Williams, Evan G., Ashbrook, David G., Roy, Suheeta, Williams, Robert W., Mozhui, Khyobeni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511861/
https://www.ncbi.nlm.nih.gov/pubmed/32790008
http://dx.doi.org/10.1111/acel.13207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511861/
https://www.ncbi.nlm.nih.gov/pubmed/32790008
http://dx.doi.org/10.1111/acel.13207

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