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Body weight and high‐fat diet are associated with epigenetic aging in female members of the BXD murine family
DNA methylation (DNAm) is shaped by genetic and environmental factors and modulated by aging. Here, we examine interrelations between epigenetic aging, body weight (BW), and life span in 12 isogenic strains from the BXD family of mice that exhibit over twofold variation in longevity. Genome‐wide DNA...
Autores principales: | Sandoval‐Sierra, Jose Vladimir, Helbing, Alexandra H. B., Williams, Evan G., Ashbrook, David G., Roy, Suheeta, Williams, Robert W., Mozhui, Khyobeni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511861/ https://www.ncbi.nlm.nih.gov/pubmed/32790008 http://dx.doi.org/10.1111/acel.13207 |
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