Dependence of PINK1 accumulation on mitochondrial redox system

Accumulation of PINK1 on the outer mitochondrial membrane (OMM) is necessary for PINK‐mediated mitophagy. The proton ionophores, like carbonyl cyanide m‐chlorophenylhydrazone (CCCP) and carbonyl cyanide‐4‐(trifluoromethoxy)phenylhydrazone (FCCP), inhibit PINK1 import into mitochondrial matrix and in...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Zhang, Yan, Hou, Xiaoou, Tao, Zhouteng, Ren, Haigang, Wang, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511888/
https://www.ncbi.nlm.nih.gov/pubmed/32779864
http://dx.doi.org/10.1111/acel.13211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511888/
https://www.ncbi.nlm.nih.gov/pubmed/32779864
http://dx.doi.org/10.1111/acel.13211

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