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Complex genetic encoding of the hepatitis B virus on-drug persistence

Tenofovir disoproxil fumarate (TDF) is one of the nucleotide analogs capable of inhibiting the reverse transcriptase (RT) activity of HIV and hepatitis B virus (HBV). There is no known HBV resistance to TDF. However, detectable variation in duration of HBV persistence in patients on TDF therapy sugg...

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Detalles Bibliográficos
Autores principales: Thai, Hong, Lara, James, Xu, Xiaojun, Kitrinos, Kathryn, Gaggar, Anuj, Chan, Henry Lik Yuen, Xia, Guo-liang, Ganova-Raeva, Lilia, Khudyakov, Yury
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511938/
https://www.ncbi.nlm.nih.gov/pubmed/32968103
http://dx.doi.org/10.1038/s41598-020-72467-9