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Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron
The consumption of red meat is probably carcinogenic to humans and is associated with an increased risk to develop colorectal cancer (CRC). Red meat contains high amounts of heme iron, which is thought to play a causal role in tumor formation. In this study, we investigated the genotoxic and cytotox...
Autores principales: | Seiwert, Nina, Wecklein, Sabine, Demuth, Philipp, Hasselwander, Solveig, Kemper, Talke A., Schwerdtle, Tanja, Brunner, Thomas, Fahrer, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511955/ https://www.ncbi.nlm.nih.gov/pubmed/32968051 http://dx.doi.org/10.1038/s41419-020-02950-8 |
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