Engineering of Long-Circulating Peptidoglycan Hydrolases Enables Efficient Treatment of Systemic Staphylococcus aureus Infection

Staphylococcus aureus is a human pathogen causing life-threatening diseases. The increasing prevalence of multidrug-resistant S. aureus infections is a global health concern, requiring development of novel therapeutic options. Peptidoglycan-degrading enzymes (peptidoglycan hydrolases, PGHs) have eme...

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Detalles Bibliográficos
Autores principales: Sobieraj, Anna M., Huemer, Markus, Zinsli, Léa V., Meile, Susanne, Keller, Anja P., Röhrig, Christian, Eichenseher, Fritz, Shen, Yang, Zinkernagel, Annelies S., Loessner, Martin J., Schmelcher, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512550/
https://www.ncbi.nlm.nih.gov/pubmed/32963004
http://dx.doi.org/10.1128/mBio.01781-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512550/
https://www.ncbi.nlm.nih.gov/pubmed/32963004
http://dx.doi.org/10.1128/mBio.01781-20

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