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Engineering of Long-Circulating Peptidoglycan Hydrolases Enables Efficient Treatment of Systemic Staphylococcus aureus Infection

Staphylococcus aureus is a human pathogen causing life-threatening diseases. The increasing prevalence of multidrug-resistant S. aureus infections is a global health concern, requiring development of novel therapeutic options. Peptidoglycan-degrading enzymes (peptidoglycan hydrolases, PGHs) have eme...

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Detalles Bibliográficos
Autores principales:	Sobieraj, Anna M., Huemer, Markus, Zinsli, Léa V., Meile, Susanne, Keller, Anja P., Röhrig, Christian, Eichenseher, Fritz, Shen, Yang, Zinkernagel, Annelies S., Loessner, Martin J., Schmelcher, Mathias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512550/ https://www.ncbi.nlm.nih.gov/pubmed/32963004 http://dx.doi.org/10.1128/mBio.01781-20

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