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Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum

A longstanding conundrum in Treponema pallidum biology concerns how the spirochete generates sufficient energy to fulfill its complex pathogenesis processes during human syphilitic infection. For decades, it has been assumed that the bacterium relies solely on glucose catabolism (via glycolysis) for...

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Detalles Bibliográficos
Autores principales: Deka, Ranjit K., Liu, Wei Z., Norgard, Michael V., Brautigam, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7512555/
https://www.ncbi.nlm.nih.gov/pubmed/32963009
http://dx.doi.org/10.1128/mBio.02249-20