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Quantum Dynamics and Non-Local Effects Behind Ion Transition States during Permeation in Membrane Channel Proteins

We present a comparison of a classical and a quantum mechanical calculation of the motion of K(+) ions in the highly conserved KcsA selectivity filter motive of voltage gated ion channels. We first show that the de Broglie wavelength of thermal ions is not much smaller than the periodic structure of...

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Detalles Bibliográficos
Autores principales: Summhammer, Johann, Sulyok, Georg, Bernroider, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513082/
https://www.ncbi.nlm.nih.gov/pubmed/33265647
http://dx.doi.org/10.3390/e20080558