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Unprecedented Regio- and Stereoselective Synthesis of Pyrene-Grafted Dispiro[indoline-3,2′-pyrrolidine-3′,3″-indolines]: Expedient Experimental and Theoretical Insights into Polar [3 + 2] Cycloaddition

[Image: see text] A series of dispiro[indoline-3,2′-pyrrolidine-3′,3″-indolines] was synthesized via a multicomponent polar [3 + 2] cycloaddition (32CA) reaction of isatin derivatives, sarcosine and (E)-3-(2-oxo-2-(pyren-1-yl)ethylidene)indolin-2-one derivatives. The regio- and stereochemistries of...

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Detalles Bibliográficos
Autores principales: Hussein, Essam M., El Guesmi, Nizar, Moussa, Ziad, Pal, Uttam, Pal, Samir K., Saha Dasgupta, Tanusri, Ahmed, Saleh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513337/
https://www.ncbi.nlm.nih.gov/pubmed/32984730
http://dx.doi.org/10.1021/acsomega.0c03510