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Chiral Chromatographic Isolation on Milligram Scale of the Human African Trypanosomiasis Treatment d- and l-Eflornithine

[Image: see text] Eflornithine is a recommended treatment against the otherwise fatal parasitic disease late stage human African trypanosomiasis (HAT), also known as Gambian sleeping sickness. It is administered repeatedly as a racemic mixture intravenously (IV) together with oral nifurtimox. Racemi...

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Detalles Bibliográficos
Autores principales: Boberg, Mikael, Jonson, Anna C., Leek, Hanna, Jansson-Löfmark, Rasmus, Ashton, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513348/
https://www.ncbi.nlm.nih.gov/pubmed/32984708
http://dx.doi.org/10.1021/acsomega.0c03121