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Interferon-beta enhances sensitivity to gemcitabine in pancreatic cancer
BACKGROUND: Adjuvant gemcitabine for pancreatic cancer has limited efficacy in the clinical setting. Impaired drug metabolism is associated with treatment resistance. We aimed to evaluate the chemosensitising effect of interferon-beta (IFN-β). METHODS: BxPC-3, CFPAC-1, and Panc-1 cells were pre-trea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513525/ https://www.ncbi.nlm.nih.gov/pubmed/32967656 http://dx.doi.org/10.1186/s12885-020-07420-0 |