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Gene flow as a simple cause for an excess of high‐frequency‐derived alleles

Most human populations exhibit an excess of high‐frequency variants, leading to a U‐shaped site‐frequency spectrum (uSFS). This pattern has been generally interpreted as a signature of ongoing episodes of positive selection, or as evidence for a mis‐assignment of ancestral/derived allelic states, bu...

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Detalles Bibliográficos
Autores principales: Marchi, Nina, Excoffier, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513730/
https://www.ncbi.nlm.nih.gov/pubmed/33005222
http://dx.doi.org/10.1111/eva.12998