Growth-factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development

Precise control and maintenance of population size is fundamental for organismal development and homeostasis. The three cell types of the mammalian blastocyst are generated in precise proportions over a short time, suggesting a mechanism to ensure a reproducible outcome. We developed a minimal mathe...

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Detalles Bibliográficos
Autores principales: Saiz, Néstor, Mora-Bitria, Laura, Rahman, Shahadat, George, Hannah, Herder, Jeremy P, Garcia-Ojalvo, Jordi, Hadjantonakis, Anna-Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513828/
https://www.ncbi.nlm.nih.gov/pubmed/32720894
http://dx.doi.org/10.7554/eLife.56079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513828/
https://www.ncbi.nlm.nih.gov/pubmed/32720894
http://dx.doi.org/10.7554/eLife.56079

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