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The E2F1 transcription factor and RB tumor suppressor moonlight as DNA repair factors

The E2F1 transcription factor and RB tumor suppressor are best known for their roles in regulating the expression of genes important for cell cycle progression but, they also have transcription-independent functions that facilitate DNA repair at sites of damage. Depending on the type of DNA damage,...

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Detalles Bibliográficos
Autores principales: Manickavinayaham, Swarnalatha, Velez-Cruz, Renier, Biswas, Anup K., Chen, Jie, Guo, Ruifeng, Johnson, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513849/
https://www.ncbi.nlm.nih.gov/pubmed/32787501
http://dx.doi.org/10.1080/15384101.2020.1801190