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Chimera RNA interference knockdown of γ-synuclein in human cortical astrocytes results in mitotic catastrophe

Elevated levels of γ-synuclein (γ-syn) expression have been noted in the progression of glioblastomas, and also in the cerebrospinal fluid of patients diagnosed with neurodegenerative diseases. γ-Syn can be either internalized from the extracellular milieu or expressed endogenously by human cortical...

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Detalles Bibliográficos
Autores principales: Le, Timmy, Winham, Cynthia L., Andromidas, Fotis, Silver, Adam C., Jellison, Evan R., Levesque, Aime A., Koob, Andrew O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513975/
https://www.ncbi.nlm.nih.gov/pubmed/32246638
http://dx.doi.org/10.4103/1673-5374.280329