Cargando…
Chimera RNA interference knockdown of γ-synuclein in human cortical astrocytes results in mitotic catastrophe
Elevated levels of γ-synuclein (γ-syn) expression have been noted in the progression of glioblastomas, and also in the cerebrospinal fluid of patients diagnosed with neurodegenerative diseases. γ-Syn can be either internalized from the extracellular milieu or expressed endogenously by human cortical...
Autores principales: | Le, Timmy, Winham, Cynthia L., Andromidas, Fotis, Silver, Adam C., Jellison, Evan R., Levesque, Aime A., Koob, Andrew O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513975/ https://www.ncbi.nlm.nih.gov/pubmed/32246638 http://dx.doi.org/10.4103/1673-5374.280329 |
Ejemplares similares
-
The Synucleins and the Astrocyte
por: Myers, Abigail J., et al.
Publicado: (2023) -
The Astrogenic Balance in the Aging Brain
por: Andromidas, Fotis, et al.
Publicado: (2021) -
Involvement of autophagy in the outcome of mitotic catastrophe
por: Sorokina, Irina V., et al.
Publicado: (2017) -
Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance
por: Streubel-Gallasch, Linn, et al.
Publicado: (2021) -
Role of senescence and mitotic catastrophe in cancer therapy
por: Singh, Richa, et al.
Publicado: (2010)