Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models

Anaplastic thyroid cancer (ATC) is a rare, but nearly uniformly fatal disease that is typically resistant to chemotherapy and radiation. Alternative strategies to target this cancer at a molecular level are necessary in order to improve dismal outcomes for ATC patients. We examined the effects of fl...

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Detalles Bibliográficos
Autores principales: Pinto, Nicole, Prokopec, Stephenie D., Ghasemi, Farhad, Meens, Jalna, Ruicci, Kara M., Khan, Imran M., Mundi, Neil, Patel, Krupal, Han, Myung W., Yoo, John, Fung, Kevin, MacNeil, Danielle, Mymryk, Joe S., Datti, Alessandro, Barrett, John W., Boutros, Paul C., Ailles, Laurie, Nichols, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514001/
https://www.ncbi.nlm.nih.gov/pubmed/32970704
http://dx.doi.org/10.1371/journal.pone.0239315