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Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models
Anaplastic thyroid cancer (ATC) is a rare, but nearly uniformly fatal disease that is typically resistant to chemotherapy and radiation. Alternative strategies to target this cancer at a molecular level are necessary in order to improve dismal outcomes for ATC patients. We examined the effects of fl...
Autores principales: | Pinto, Nicole, Prokopec, Stephenie D., Ghasemi, Farhad, Meens, Jalna, Ruicci, Kara M., Khan, Imran M., Mundi, Neil, Patel, Krupal, Han, Myung W., Yoo, John, Fung, Kevin, MacNeil, Danielle, Mymryk, Joe S., Datti, Alessandro, Barrett, John W., Boutros, Paul C., Ailles, Laurie, Nichols, Anthony C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514001/ https://www.ncbi.nlm.nih.gov/pubmed/32970704 http://dx.doi.org/10.1371/journal.pone.0239315 |
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