Prolonged infection triggered by dormant Mycobacterium tuberculosis: Immune and inflammatory responses in lungs of genetically susceptible and resistant mice

We developed an approach for substantial attenuation of Mycobacterium tuberculosis by prolonged culturing under gradually acidifying conditions. Bacteria subjected to acidification lost the capacity to form colonies on solid media, but readily resuscitated their growth in the murine host, providing...

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Detalles Bibliográficos
Autores principales: Kondratieva, Tatiana, Shleeva, Margarita, Kapina, Marina, Rubakova, Elvira, Linge, Irina, Dyatlov, Alexander, Kondratieva, Elena, Kaprelyants, Arseny, Apt, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514034/
https://www.ncbi.nlm.nih.gov/pubmed/32970762
http://dx.doi.org/10.1371/journal.pone.0239668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514034/
https://www.ncbi.nlm.nih.gov/pubmed/32970762
http://dx.doi.org/10.1371/journal.pone.0239668

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