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Genetic buffering and potentiation in metabolism
Cells adjust their metabolism in response to mutations, but how this reprogramming depends on the genetic context is not well known. Specifically, the absence of individual enzymes can affect reprogramming, and thus the impact of mutations in cell growth. Here, we examine this issue with an in silic...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514045/ https://www.ncbi.nlm.nih.gov/pubmed/32925942 http://dx.doi.org/10.1371/journal.pcbi.1008185 |