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Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock

Genome-Wide Association Studies (GWAS) in large human cohorts have identified thousands of loci associated with complex traits and diseases. For identifying the genes and gene-associated variants that underlie complex traits in livestock, especially where sample sizes are limiting, it may help to in...

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Detalles Bibliográficos
Autores principales: Raymond, Biaty, Yengo, Loic, Costilla, Roy, Schrooten, Chris, Bouwman, Aniek C., Hayes, Ben J., Veerkamp, Roel F., Visscher, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514049/
https://www.ncbi.nlm.nih.gov/pubmed/32925905
http://dx.doi.org/10.1371/journal.pgen.1008780