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Bio-activating ultrafine grain titanium: RNA sequencing reveals enhanced mechano-activation of osteoconduction on nanostructured substrates

Titanium is essentially absent from biological systems yet reliably integrates into bone. To achieve osseointegration, titanium must activate biological processes without entering cells, defining it as a bio-activating material. Nanostructuring bulk titanium reduces grain size, increases strength, a...

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Detalles Bibliográficos
Autores principales: Reiss, Rebecca A., Lowe, Terry C., Sena, Johnny A., Makhnin, Oleg, Connick, Melanie C., Illescas, Patrick E., Davis, Casey F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514099/
https://www.ncbi.nlm.nih.gov/pubmed/32970688
http://dx.doi.org/10.1371/journal.pone.0237463