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Bio-activating ultrafine grain titanium: RNA sequencing reveals enhanced mechano-activation of osteoconduction on nanostructured substrates
Titanium is essentially absent from biological systems yet reliably integrates into bone. To achieve osseointegration, titanium must activate biological processes without entering cells, defining it as a bio-activating material. Nanostructuring bulk titanium reduces grain size, increases strength, a...
Autores principales: | Reiss, Rebecca A., Lowe, Terry C., Sena, Johnny A., Makhnin, Oleg, Connick, Melanie C., Illescas, Patrick E., Davis, Casey F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514099/ https://www.ncbi.nlm.nih.gov/pubmed/32970688 http://dx.doi.org/10.1371/journal.pone.0237463 |
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