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Entropy and Information within Intrinsically Disordered Protein Regions

Bioinformatics and biophysical studies of intrinsically disordered proteins and regions (IDRs) note the high entropy at individual sequence positions and in conformations sampled in solution. This prevents application of the canonical sequence-structure-function paradigm to IDRs and motivates the de...

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Detalles Bibliográficos
Autores principales: Pritišanac, Iva, Vernon, Robert M., Moses, Alan M., Forman Kay, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515160/
https://www.ncbi.nlm.nih.gov/pubmed/33267376
http://dx.doi.org/10.3390/e21070662