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Kinetic modeling of H(2)O(2) dynamics in the mitochondria of HeLa cells

Hydrogen peroxide (H(2)O(2)) promotes a range of phenotypes depending on its intracellular concentration and dosing kinetics, including cell death. While this qualitative relationship has been well established, the quantitative and mechanistic aspects of H(2)O(2) signaling are still being elucidated...

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Detalles Bibliográficos
Autores principales: Stein, Kassi T., Moon, Sun Jin, Nguyen, Athena N., Sikes, Hadley D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515204/
https://www.ncbi.nlm.nih.gov/pubmed/32925922
http://dx.doi.org/10.1371/journal.pcbi.1008202