Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases

Patients with colorectal liver metastases (CLM) commonly receive neoadjuvant chemotherapy (NACT) prior to surgical resection. NACT may induce immunogenic cell death with subsequent recruitment of T-cells to the tumor microenvironment, which could be exploited by immune checkpoint inhibition (ICI). I...

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Detalles Bibliográficos
Autores principales: Dagenborg, Vegar Johansen, Marshall, Serena Elizabeth, Yaqub, Sheraz, Grzyb, Krzysztof, Boye, Kjetil, Lund-Iversen, Marius, Høye, Eirik, Berstad, Audun E, Fretland, Åsmund Avdem, Edwin, Bjørn, Ree, Anne Hansen, Flatmark, Kjersti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515522/
https://www.ncbi.nlm.nih.gov/pubmed/32098573
http://dx.doi.org/10.1080/15384047.2020.1721252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515522/
https://www.ncbi.nlm.nih.gov/pubmed/32098573
http://dx.doi.org/10.1080/15384047.2020.1721252

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